Here's a look at Karl Rove's latest US Senate race map . As you can see, there's a lotta' red there. And, of course, keep in mind that Massachusetts was "solid blue" just two weeks ago.
Larry Sabato  also has a list of current projections up on Rasmussen's site. He's currently showing a 7 seat gain for the GOP, for what it's worth.
Of course all this stuff can change in a heart beat one way or another, (as Scott Brown demonstrated). And the election is a full 9 months away...which is an eternity in politics. But given the current environment...and if the GOP puts up the right candidates which stick to a real conservative message, it should be a good November.